A Canadian team has harnessed genealogical data from Quebec to retrace the history of a rare recessive disease called “chronic atrial and intestinal dysrhythmia” (CAID), using a computational approach for inferring rare allele transmission history.

Researchers from McGill University and elsewhere used their software package, known as ISGen, to analyze past transmission of CAID alleles with the help of high-quality genealogical data for more than 3.4 million individuals of European ancestry in the Canadian province.

Monday 10 to Friday 14 December:Preservation Week at PRONI. The Public Record Office of NI is holding its annual behind-the-scenes event. Document ordering and production will be suspended throughout the week, but the Search Room and self-service microfilm facilities will be available as normal. No 'late-night Thursday'. Monday 10 December:NLI Reading Room and Manuscript Room closed all day. Venue: National Library of Ireland, Kildare Street, Dublin 2.

Josh Duhamel, “Transformers” star, will be featured in this Tuesday’s edition of the U.S. version of Who Do You Think You Are? The show is broadcast on TLC, available primarily on cable and satellite television services as well as on a delayed basis in the future on the program’s web site at: https://www.tlc.com/tv-shows/who-do-you-think-you-are.

Last week’s episode with Mandy Moore is now available online at the same web address: https://www.tlc.com/tv-shows/who-do-you-think-you-are.

You can check it out at: http://www.godfrey.org:

IrishGenealogy.ie is offline this morning. Before you go getting all excited and start reserving your research hours for an imminent upload of records, I can tell you that the temporary disappearance of the site is due to a technical fault.

The techies are now working on it, and hopefully the site will be up and running later today.

As to the long-awaited upload, a seasonal gift to researchers is not in the offing.